Research Journal of Pharmacology and Pharmacodynamics

Shashi Kala Dhruv (Thakur) ¹, A. Bansal ², V. K. Dhruv ², P. K. Kar ², H. B. Rathi ², P. K. Shrivastava ²

Affiliations
1 Dept. of Pathology, Govt. Medical College, Jagdalpur, (Bastar) - 494001, IN
2 Govt. Medical College, Jagdalpur, (Bastar) - 494001, IN

Abstract

Back ground: The distress, pain and struggle through a difficult labour is neither well tolerated by patients nor appreciated by Obstetrician. So use of Caesarean Section to terminate painful and difficult labour has increased the incidence tremendously. Objective: the objective was to study the determinants of Caesarian Section among mothers under gone the procedure. Material and Methods: The mothers under gone Caesarean Section in a medical college hospital. Study variables included mother's age, weight, Gravida, Gestational age, Basal pulse rate , Mean arterial pressure in mm. Hg., prity, history of previous Caesarean Section in earlier delivery. Statistical Analysis: The results were expressed in terms of mean ± SE_M and proportion as and when required. Observations: Highest percentage of caesarean section has the previous history of the procedure in earlier delivery which was in accordance of the adage "once a caesarean always a caesarean". Vertex was the commonest presentation (81.11 %).Conclusion: The mothers who are at risk for Caesarean should be identified and high quality ante natal care should be given in order to minimize the complications of the procedure. As an unnecessary surgery is jeopardizing women's health, hence before recommending the procedure, all alternative method must be explored.

Keywords

Caesarean, Presentation, Mean.

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V. K. Dhruv ¹, Sanat Singh ², A. K. Bansal ², P. K. Shrivastava ², Raj Sharma ²

Affiliations
1 Govt. Medical College, Dept. of Anesthesia1, Jagdalpur (Bastar) 494001, IN
2 Govt. Medical College, Jagdalpur (Bastar) 494001, IN

Abstract

On analysis of the collected data, it has been revealed that in study group, there was rise, fall and no change in pulse rate of 56.66, 11.66 and 31.66% patients in comparison to 84.0, 12.0 and only 4.0 patients of control group respectively. Regarding effect on B.P. of study group in comparison to control group, a significant difference in fall of B.P. was noted, regarding increase in B.P., the difference found statistically insignificant. Thus Pipe curenium bromide has been found to be cardiovascular stable muscle relaxant.

Keywords

Pulse Rate, Blood Pressure.

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V. K. Dhruv ¹, A. Sahu ², A. K. Bansal ³, Shashi Kala Dhruv (Thakur) ⁴, B. Baghel ⁵, K. K. Viswanadham ⁵, Bithika Nel Kumar ⁶

Affiliations
1 Dept. of Anaesthesia, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN
2 Dept. of Paediatrics, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN
3 Dept. of Community Medicine, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN
4 Dept. of Pathology, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN
5 Dept. of Paediatrics, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN
6 Dept. of Pharmacology, Govt. Medical College, Jagdalpur (BASTAR) - 494001, IN

Abstract

Background: For Caesrian section to provide optimal anaesthesia, causing less transpass in to the existing patho-physiology of the mother and child, needs the use of such technique and drugs which have minimal side effects. Research question: Use of Pipe curonium Bromide as an anaesthetic agent, has any bearing, on neonates using Neurological Adaptive Capacity Score. Material and Methods: New Bornes of 85 mothers who have under gone elective and emergency L.S.C.S. were included in the study. Observations: 85%of newborns had an average N.A.C.S. score of 35.37 at 15 minutes, 38.46 to 39.90 at 2 hours and 24 hours intervals, there by depiciting a vigorous neonate with no evidence of cardio respiratory depression or residual effects of neuromuscular blocks drugs. Conclusion: Pipecuronium Bromide is a good muscle relaxant as evaluated by N.A.C.S. System.

Keywords

Muscle Relaxant, New Borne.

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